Olivia earned her PhD in Neuroscience from the Ruhr University Bochum. Originally trained as an electrophysiologist, she later expanded her expertise to optogenetics, protein design, circuits neuroscience, behavior and machine learning methods. After a reserach stay in the Laboratoire de Neurobiologie des Reseaux Sensorimoteurs, Université Paris Descartes, Paris, France, Olivia began her postdoctoral research in the lab of Stefan Herlitze and later became a junior group leader and assistant professor for advanced fluorescence microscopy at the Ruhr University Bochum. She then accepted a position as an associate professor for Synthetic Biology at the University of Bremen. Now, Olivia leads the Neuromodulatory Circuits Lab at the University of Cologne.
Martin grew up in Ibbenbüren, Germany, and earned his BSc at Ruhr-Universität Bochum. He continued his studies there, completing his MSc in the lab of Stefan Herlitze, where he worked on the development of optogenetic tools for neuronal inhibition.
For his PhD, Martin joined the Masseck Lab, shifting his focus from neuronal manipulation to detecting serotonin release. During this time, he developed the serotonin sensor sDarken. His research interests remain centered on fluorescent biosensors, particularly for serotonin.
Juli grew up near Bonn, Germany, and earned her BSc in Applied Biology from the University of Applied Sciences in Rheinbach. She then pursued an MSc in Neurosciences at the University of Bremen, where she completed her thesis in the Masseck Lab, developing an optogenetic tool to control mitochondrial movement in vitro.
Continuing her research in the Masseck Lab, Juli transitioned from molecular approaches to in vivo electrophysiology in mice. Her doctoral research integrates optogenetics, electrophysiology, and behavioral studies to investigate the role of serotonin within the corticolimbic circuit in a mouse model of depression.
Maja grew up in Stuttgart, Germany, and holds a BSc in Psychology from the University of Tübingen. She later pursued her MSc in Neurosciences at the University of Bremen, where she completed her thesis under the guidance of Sami Hassan, focusing on modelling learning strategies using a Bayesian framework. Following her passion for statistics and computational methods, she joined the Masseck Lab in November 2024. Her doctoral research aims to investigate the influence of neuromodulation on latent neural representations.
Ryan grew up in Seattle, Washington, USA and obtained a BSc in Molecular Biology at the University of Wyoming with a capstone project exploring mutations in aceK∆ Escherichia coli that restore glyoxylate bypass activity. He then moved on to the University of Bremen where he earned an MSc in Neuroscience, with a thesis in Prof. Dr. Olivia Masseck’s lab focusing on developing the mScarlet based calcium indicator PinkyCaMP. As a PhD student, he continues to improve PinkyCaMP as well as developing new mScarlet based biosensors for intensity and FLIM measurements, with an emphasis on GPCR based sensors.
Niklas will start his PhD in June in the Masseck Lab, and we are very much looking forward to welcoming him to our team!
Born in Syke, Niklas began his career as a surgical assistant in neurosurgery before embarking on his academic journey. He earned his Bachelor's degree in Molecular Biology and Biochemistry from the University of Kiel and continued his studies with a Master's degree in Neuroscience at the University of Bremen. During his Master's program, he engineered optogenetic serotonergic receptor chimeras, demonstrating his commitment to innovative research. He then contributed to the development of advanced multi-component optogenetic tools in Vierock's Subcellular Optogenetics Lab at the Charite Berlin. In his PhD Niklas will focuses on developing innovative sensors and optogenetic tools.
Arne grew up near Brunswick, Germany, and earned a BSc in Psychology from the University of Bremen. His passion for biological psychology led him to continue his studies in Bremen, where he pursued an MSc in Neurosciences, specializing in systems neuroscience under the mentorship of Sami Hassan. For his thesis, he explored the serotonergic modulation of hippocampal spatial coding properties, employing miniscope imaging in freely behaving mice. Arne will join the Masseck lab in May 2025, bringing his enthusiasm for optophysiological techniques, and pharmacological manipulation. His doctoral research aims to investigate the effects of new psychoactive substances (NPS) on serotonin and norepinephrine dynamics, highlighting their therapeutic potential in a mouse model of depression.
Svenja grew up in a town near Dortmund, Germany, and began her academic journey through a second-chance education. She earned her BSc in Biology from Ruhr-Universität Bochum, where she developed a strong interest in neuroscience, particularly in optogenetics and serotonin signaling in psychiatric disorders. For her undergraduate thesis in the lab of Stefan Herlitze, she engineered a light-activated 5-HT receptor chimera and characterized its function using electrophysiology.
During her MSc in Neuroscience in the Masseck lab, Svenja employed optogenetics to study anxiety behavior in mice. During her Master’s thesis, she even relocated with the Masseck Lab to Bremen, where she began later on her PhD research. Her doctoral work focuses on the role of astrocytic serotonin signaling in the medial prefrontal cortex in depression, utilizing a combination of optogenetics, imaging, and electrophysiology.
Imandra grew up in Berlin, Germany. She studied Biology at the University of Bremen, where she later also completed her MSc in Neuroscience. For her Master’s thesis, she returned to Berlin to work on an electrophysiology project at the Charité.
After earning her MSc degree, she gained experience working in a medical laboratory in Bremen before starting her PhD in the Masseck lab. Her doctoral research focuses on the heterodimerization and interaction of serotonin receptors, aiming to provide fundamental insights that could contribute to the development of more effective treatments for neuropsychiatric disorders.
Girona is a trained search and rescue dog who received her training at a rescue dog unit. She makes sure that each lab member takes short breaks to cuddle her.
Kim was a valued member of the Masseck Lab and is currently in the final stages of submitting her PhD thesis—formerly known as "Pinky and the Brain." Fingers crossed!
In her PhD research, Kim investigated the NEX-Cre transgenic mouse line, a widely used tool in neuroscience for targeted genetic modifications. While previous studies suggested that this strain exhibits no behavioral or histological abnormalities, her work uncovered distinct behavioral changes, including reduced anxiety, anhedonia-like traits, and increased motor activity, as well as dendritic spine abnormalities in several brain regions. These findings emphasize the importance of thoroughly characterizing transgenic models to ensure their reliability in scientific research.
Kim also made a significant contribution to our latest PinkyCaMP publication.
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